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Correlated with the onset of storage protein synthesis, there is a large increase in the numbers of membrane bound ribosomes, but the numbers of free3ribosomes remain approximately constant. Experiments with ( H) uridine show that there is no interconversion of these two classes of ribosomes, and both were shown to incorporate amino acids “in vivo”. Experiments with ( P) ortho phosphate indicate that these ribosomes are synthesised “de novo”, rather than being formed by the attachment of pre existing, free ribosomes to membranes.

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